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Inventi Impact: Med Chem

Articles

  • Inventi:pmc/25592/18
    Synthesis, Characterization, and Antimicrobial Activity of a Novel Trisazo Dye from 3-Amino-4Hthieno[\n3,4-c][1]benzopyran-4-one
    01-Jan-1970 Research 2018 : April - June
    Joseph Tsemeugne, Emmanuel Sopbue Fondjo, Jean-de-Dieu Tamokou, Taoufik Rohand, Arnaud Djintchui Ngongang, Jules Roger Kuiate, Beibam Luc Sondengam

    A new trisazo dye has been synthesized by coupling the diazonium ion of 3-amino-4H thieno[3,4-c][1]benzopyran-4-one with 2-\ntert-butyl-4-methoxyphenol. The newly prepared trisazo dye was characterized by its physical, elemental, and spectroscopic data.\n2D-NMR (COSY, HSQC, and HMBC) techniques were used to secure the structural assignments. The new trisazo dye (compound\n7) along with precursors 3, 4, and 6 was screened by microdilution susceptibility assay for antibacterial and antifungal activities\ntowards eight bacterial strains and three yeasts selected on the basis of their relevance as human pathogens. The results showed that\ncompound 7 (MIC = 2ââ?¬â??128

    How to Cite this Article
    CC Compliant Citation: Joseph Tsemeugne, Emmanuel Sopbué\nFondjo, Jean-de-Dieu Tamokou, et al., â??Synthesis, Characterization,\nand Antimicrobial Activity of a Novel Trisazo Dye from 3-\nAmino-4H-thieno[3,4-c][1]benzopyran-4-one,â? International\nJournal of Medicinal Chemistry, vol. 2018, Article ID 9197821, 8\npages, 2018. doi:10.1155/2018/9197821, https://\ncreativecommons.org/licenses/by/4.0/.
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